8M NIH grant supports multi-center.

$23.8M NIH grant supports multi-center, multidisciplinary study about deadly bleeding syndrome A new five-year, $23 articles .8 million National Institutes of Health grant will support a multi-center, multidisciplinary study on a deadly bleeding syndrome – called coagulopathy – occurring without warning in a few trauma sufferers. Led by University of Vermont Professor Emeritus of Biochemistry Kenneth Mann, Ph.D., the TACTIC research is a cooperative work funded by the National Center, Lung and Blood Institute that establishes a distinctive collaboration between the NIH and the Division of Defense.

Study Outcomes Gestational hypertension or preeclampsia was diagnosed in 53 women at 28 hospitals . The risk of this outcome was higher among donors than among nondonors . Each element of the primary outcome was also more prevalent among donors . The two groups didn’t differ significantly regarding various other secondary maternal or fetal outcomes. There have been no maternal deaths, stillbirths, or neonatal deaths in either group. Subgroup and Additional Analyses In subgroup analyses, the odds ratio for the primary outcome in donors as compared with nondonors was significantly higher among women who were more than 32 years of age than among those who were 32 years or younger . In extra analyses, among both nondonors and donors, gestational hypertension or preeclampsia was connected with an increased likelihood of cesarean section or low birth pounds .