Akonni receives NSFs Phase 2 SBIR Grant to develop Lab-on-a-Film microarray Akonni Biosystems.

Akonni receives NSF’s Phase 2 SBIR Grant to develop Lab-on-a-Film microarray Akonni Biosystems, a lifestyle science tools molecular diagnostics company / that develops, manufactures, and programs to market molecular testing products for diagnosing infectious diseases and individual genetic disorders, announced today the receipt of a $498,780 Phase 2 SBIR Grant from the National Science Base . This second circular of funding from NSF will enable Akonni to develop its Lab-on-a-Film microarray further consumable that can be produced on ultra-low-cost film using a highly automated, reel-to-reel production procedure.Based on this level of power and performance, the experts concluded the Individual Transcriptome Array is even more reproducible, faster, and cost-effective than RNA-Seq for characterizing and detecting low-level expression changes of clinically relevant transcripts. ‘An emerging approach for large-scale clinical genomic studies is to first make use of RNA-Seq to the adequate depth of 200 million or greater reads for the discovery of transcriptome components relevant to the disease process, followed by dependable and high-throughput screening of the elements on thousands of patient samples using custom made designed arrays,’ added Dr. Davis, winner of this year’s Gruber Genetics Prize for distinguished contributions to genetics research. ‘Experts and clinicians are demanding solutions like our fresh array to go beyond simply identifying transcripts, to measuring the differences within their abundance in huge clinical studies actually.’ The new array may be the 6.9 million-feature Glue Grant Individual Transcriptome Array developed with Stanford as part of the NIH Glue Grants plan, a three-year multicenter effort to answer clinical questions needing a translational bench to bedside technique.